Pricing
We charge for outcomes, not hours. No change orders, no material pass-throughs, no additional fees.
Bioanalysis Assays
Sample analysis pricing is all-inclusive. The price includes labor, equipment, reagents, consumables, reporting, data transfer, and any required retesting. Standard liquid biomatrices are supported: serum, plasma, urine, and tissue homogenate. Soft tissues are also supported with an additional homogenization fee (see below). All assays in their standard configuration have a minimum batch charge equivalent to 30 samples.
ELISA
$90/sample
- Measurements performed in duplicate.
- Pricing reflects single analyte.
- Typical minimum sample volume of 50 µL.
MSD
$95/sample
- Measurements performed in duplicate.
- Pricing reflects single analyte. Multiplex assays charged at $4.50/sample for each additional analyte.
- Typical minimum sample volume of 50 µL.
LC-MS
$90/sample
- Measurements performed in singlet.
- Includes sample preparation prior to injection.
- Typical minimum sample volume of 75 µL.
- Additional multiplex analytes charged at $5/sample.
qPCR
$45/sample
- Measurements performed in triplicate.
- Typical minimum sample volume of 10 µL.
- Nucleic acid extraction is included in the price.
- Additional multiplex analytes charged at $5/sample.
ADME Assays
Our ADME assays are pre-developed to support a wide array of small molecule compounds. Our default options are listed here, but each assay can be configured to your specific requirements.
Microsomal Stability
$135/sample
- Run with 1µM test compound and pooled human liver microsomes.
- Measurements in singlet at 5 timepoints (0, 5, 15, 30, and 45 mins) along with a negative cofactor control.
- Minimum charge of 30 samples per batch.
Plasma Protein Binding
$135/sample
- Performed in a Thermo Rapid Equilibrium Dialysis plate with 1µM test compound in 100% plasma.
- Measurements performed in duplicate.
- Minimum charge of 15 samples per batch.
Sample Accessioning
Accessioning involves receipt, unpacking, inspection, inventorying and relabeling and aliquoting as necessary. Compatible, pre-barcoded labware is accessioned at no charge as we are able to directly inventory and load onto our equipment.
Compatible Labware
Free
Other Labware
$10/sample
Sample Prep
We support standard sample preparation procedures priced here. We can also work with a wide array of custom sample preparation procedures tailored to your unique needs during method development.
Tissue Homogenization
$30/sample
- Most soft tissues supported including liver, kidney, lung, and heart.
- Samples must be provided in 7.6 mL Azenta or 15 mL pre-barcoded falcon tubes.
Sample Storage
We provide both short-term and long-term storage of samples following analysis. The first 90 days are complementary. Afterwards, you can elect to store your samples at Dash for a monthly fee, have them shipped or couriered back to you, or have them destroyed.
First 90 Days
Free
Long-Term Storage
$0.4/sample
- Charged monthly.
- Samples stored at -80C with 24x7 environmental monitoring.
- No charge for samples picked for additional analysis at Dash.
- Additional fees apply for picking, shipping, and destruction of samples.
Standard Method Development
Dash has predefined standard offerings to streamline method development for your project. These standard offerings include full onboarding of your assay onto our platform and optimization for your specific analyte, biomatrix, and use case. As part of development, we establish a robust procedure to reliably return results for future sample analysis: dilution level, linearity, precision, accuracy, recovery, and matrix effects.
The prices are $7k for ELISA/MSD with existing kits (plus an additional fee for multiplex MSD), $15k for LC-MS with an established protocol, and $10k for qPCR with know primers/probes. All prices are fixed and inclusive of all materials, consumables, labor, and reporting for a single analyte in a single matrix. Additional multiplex analytes, matrices, and other configurations are available for an additional fee.
Custom Method Development
We are also able to support fully custom method development. Whether you need antibodies developed for an LBA assay, primers and probes developed for a qPCR, or you don't even know where to start, Dash can support you. We have an exceptionally talented and experience scientific team who can understand the intricacies of your specific project and work with you to design a robust assay that will meet your needs.
Dash will work with you to design a quote tailored to your needs. However, we will always quote fixed, all-inclusive pricing based on mutually agreed milestones.
Method Validation
Includes full validation of assay according to GLP/GCP requirements. All materials, labor, equipment, and reporting included. Successful validation is guaranteed or there is no charge.
Note that multiplex MSD assays require an additional charge per analyte.
Frequently asked questions
The quoted pricing includes all materials (consumables and reagents), retesting/reanalyses for samples failing QC/CV or outside the quantifiable range, data analysis, data transfers, reporting, QA, and 90 days of sample storage.
Yes. As our costs are per plate, we charge for at least 30 samples for any sample analysis project. If you have fewer samples, you will be charged for a full 30 samples.
Yes. We offer discounts per sample starting at just 200 samples. Discount rates apply to samples in the given range:
- 1-200 samples: No discount
- 201-500 samples: 10% discount
- 501-1000 samples: 20% discount
- 1000+ samples: 30% discount
For example, if you submit 750 samples for a given assay, the first 200 are at full price, the next 300 are 10% off, and the final 250 are 20% off.
Additionally, with our automated platform, we are happy to work with 384-well plates, which dramatically increases throughput, reduces sample volumes, and has a lower per-sample cost than 96-well plates.
We also provide discounts for annual committed spend. Please contact us for more detail.
Yes. Dash offers a blanket 10% discount on all services for nonprofits and academic organizations. Additional discounts and credits may be offered on a case by case basis. Please contact us to discuss your specific project and circumstances.
Method development includes all phases of creating a robust and repeatable assay for a given analyte(s). This includes research, reagent/material selection (e.g. antibodies, columns), optimization of critical process parameters (e.g. pressure, temperature), establishment of calibration curve, QC levels, and LoQ/LoDs, documentation, and reporting.
Method development reports include all materials (reagents and critical consumables) and instruments as well as a full method protocol with each step and parameters sufficient to replicate elsewhere, and all data, analyses, and summary conclusions.
Method validation reports a full validation protocol, all procedures used for each validation run, all data and calculations, the performance characteristics of the assay, and conclusions.
No. If Dash has already pre-developed or validated a commonly used assay (e.g. a cytokine panel) in your biomatrix of interest, there is no additional development or validation cost. You simply pay for the analysis of your samples.
Put Dash to the test.
Curious if Dash is the right fit? Let us prove it. We’ll take on development work with a guarantee that you will only pay if we can make the assay run on our platform and meet your requirements.